Chronic stress followed by social isolation promotes depressive-like behaviour, alters microglial and astrocyte biology and reduces hippocampal neurogenesis in male mice

Publication date: Available online 2 August 2020Source: Brain, Behavior, and ImmunityAuthor(s): Andrea Du Preez, Diletta Onorato, Inez Eiben, Ksenia Musaelyan, Martin Egeland, Patricia A. Zunszain, Cathy Fernandes, Sandrine Thuret, Carmine M. Pariante
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research

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Publication date: November–December 2020Source: Heart &Lung, Volume 49, Issue 6Author(s): Linda Clements, Susan K. Frazier, Debra K. Moser, Terry A. Lennie, Misook L. Chung
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
Publication date: 1 January 2021Source: Personality and Individual Differences, Volume 168Author(s): Feizhong Zheng, Wenting Wu, Lijing Wang, Arlette J. Ngoubene-Atioky, Li Chen
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
CONCLUSION: In a NHP ARS model, sargramostim administered starting at 48 h post-radiation was effective to improve survival, while beneficial hematological effects were observed with sargramostim initiated up to 120 h post exposure. PMID: 32960660 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
In 2019, before the pandemic hit, nearly 1 in 5 adults had depression and nearly 1 in 6 had anxiety, with dramatic increases seen in 2020.Medscape Medical News
Source: Medscape FamilyMedicine Headlines - Category: Primary Care Tags: Psychiatry News Source Type: news
Authors: Ormel J, Bosker FJ, Hollon SD, Ruhe HG PMID: 32951616 [PubMed - as supplied by publisher]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
This study aims at testing in a RCT the effectiveness of a disorder-specific, Internet-delivered CBT (ICBT) intervention for AjD. Participants were randomly allocated to either an ICBT with brief weekly telephone support (n=34) or a waiting list group (n=34). Beck's inventories for depression and anxiety were used as primary outcomes. The secondary outcomes were adjustment disorder symptoms, posttraumatic growth, positive and negative affect, and quality of life. In all, 76.5% of the participants completed the intervention. Compared to the control group, participants in the intervention condition showed significantly great...
Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
We examined the association between androgen deprivation therapy (ADT) use and the risk of mild cognitive impairment (MCI) among prostate cancer patients. METHODS: We included 241 cognitively unimpaired men, aged 70 to 90, with a history of prostate cancer before enrollment in the population-based Mayo Clinic Study of Aging. Using the Rochester Epidemiology Project medical records-linkage system, ADT use and length of exposure were abstracted. Follow-up visits occurred every 15 months and MCI diagnoses were made based on clinical consensus. Cox proportional hazards models, with age as the timescale, were used to examin...
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research
CONCLUSION: Never-married status above the mean first marriage age was associated with mental disorders and suicidality. These findings suggest the need for a national strategy to develop an environment where people with never-married status do not suffer even if their marriage is delayed. PMID: 32959544 [PubMed - in process]
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Conditions:   Depression;   Anxiety;   Suicidal Ideation;   Substance Use Intervention:   Behavioral: Knowing Who You Are (Becoming): Cultural Identity Intervention Sponsors:   University of Alaska Anchorage;   National Institute of General Medical Sciences (NIGMS) Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Mild Traumatic Brain Injury;   Internet-Delivered Cognitive Behavioural Therapy;   Depression;   Anxiety Intervention:   Behavioral: Internet-delivered Cognitive Behavioural Therapy(ICBT) Sponsor:   Lawson Health Research Institute Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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