Tracheobronchial amyloidosis: an uncommon disease with a common presentation

We describe three cases who presented with haemoptysis, which on further evaluation were diagnosed as isolated tracheobronchial amyloidosis, and a review of literature. AbstractAmyloidosis is an uncommon heterogeneous and multi ‐systemic disease characterized by extracellular amyloid deposition. The size of proteins varies and forms a part of local disease or systemic process. Light chain amyloidosis (AL) is the most prevalent form of systemic amyloidosis which may also be seen in localized disease. Isolated tracheobronc hial amyloidosis (TBA) is rather unusual with local amyloid deposition which may pose a diagnostic dilemma with subsequent therapeutic challenge. Awareness of such a presentation is crucial in the diagnosis of this rare disease. We describe three cases who presented with haemoptysis, which on furthe r evaluation were diagnosed as isolated TBA, and a review of literature.

Source: Respirology Case Reports - August 1, 2020 Category: Respiratory Medicine Authors: Loveleen Mangla, Rohit Vadala, Shirish Kumar Kadli, Deepak Prajapat, Deepak Talwar Tags: Case Series Source Type: research