Upregulation of ubiquitinated proteins and their degradation pathway in muscle atrophy induced by cisplatin in mice.

In conclusion, ubiquitin and ubiquitinated proteins are upregulated in cisplatin-induced muscle atrophy. Cisplatin-induced ubiquitinated proteins are degraded by the 26 s proteasome pathway. PMID: 32738330 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32738330?dopt=Abstract

Source: Toxicology and Applied Pharmacology - July 28, 2020 Category: Toxicology Authors: Sakai H, Ikeno Y, Tsukimura Y, Inomata M, Suzuki Y, Kon R, Ikarashi N, Chiba Y, Yamada T, Kamei J Tags: Toxicol Appl Pharmacol Source Type: research