Pharmacological disinhibition enhances paced breathing following complete spinal cord injury in rats

Publication date: Available online 1 August 2020Source: Respiratory Physiology &NeurobiologyAuthor(s): T. Bezdudnaya, M.A. Lane, V. Marchenko
Source: Respiratory Physiology and Neurobiology - Category: Respiratory Medicine Source Type: research

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Publication date: Available online 28 September 2020Source: Brain, Behavior, and ImmunityAuthor(s): Jesús Amo-Aparicio, Alba Sanchez-Fernandez, Suzhao Li, Elan Z. Eisenmesser, Cecilia Garlanda, Charles A. Dinarello, Ruben Lopez-Vales
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Authors: Hassaballa D, Harvey RL Abstract The management of pain in persons with neurological injuries is challenging and complex. A holistic view and clinical approach are necessary when addressing pain in patients with neurological impairment because interpreting signs and symptoms and deciphering sources of pain is never a straightforward process. This problem is further magnified with the management of central pain syndromes. The best approach is to have a good understanding of the clinical characteristics commonly found in this patient population, in particular for patients with stroke, multiple sclerosis (MS)...
Source: NeuroRehabilitation - Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research
We describe pain intensity and interference at baseline and 1 year postinjury in burn, traumatic brain injury (TBI), and spinal cord injury (SCI) survivors and compare them with the general population (GP). We tested a custom Patient Reported Outcomes Measurement Information System (PROMIS) pain interference short form developed for use in trauma populations. METHODS We administered a pain intensity numerical rating scale and custom PROMIS pain interference short forms at baseline and/or 1 year postinjury from participants (≥18 years) at three Model System projects (burn, TBI, and SCI). Scores were compared across in...
Source: Journal of Trauma and Acute Care Surgery - Category: Surgery Tags: BRIEF REPORTS Source Type: research
Conclusions: The biomembrane barrier formed at the tumor edge after RFA can prevent bone cement leakage into the spinal canal, reducing spinal cord injury and prolonging the survival time.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
Condition:   Spinal Cord Injury at C5-C7 Level Interventions:   Other: FES+CBA;   Other: FES Sponsor:   Azienda Ospedaliero, Universitaria Pisana Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Elezanumab (ABT-555) is an investigational treatment being evaluated in neurological disorders, including treatment following spinal cord injury Orphan Drug Designation is given to a drug or biologic for the treatment, diagnosis or prevention of a rare ... Biopharmaceuticals, Neurology, FDA AbbVie, elezanumab, spinal cord injury
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
To evaluate the incidence and epidemiological characteristics of acquired nontraumatic spinal cord injury (NTSCI) in Finland.
Source: Archives of Physical Medicine and Rehabilitation - Category: Rehabilitation Authors: Source Type: research
Authors: Liao YX, He SS, He ZM Abstract Transient paralysis following spinal decompression surgery is a rare but devastating postoperative complication. Spinal cord ischemia-reperfusion injury has been identified as one of the crucial pathogenic factors contributing to the sudden neurological deterioration associated with spinal decompression surgery. 'White cord syndrome' is a characteristic imaging manifestation of spinal cord ischemia-reperfusion injury, referring to high intramedullary signal changes in the sagittal T2-weighted MRI scan with unexplained neurological deficits following surgical decompression. Th...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
CONCLUSION: In our study, 70% of the muscles with a SMMT motor response of zero and 72% of the muscles with a SMMT motor response greater than or equal to one demonstrated SA on EMG. The use of the SMMT as a clinical measure to differentiate LMN from UMN integrity may be limited when applied. PMID: 32972329 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Publication date: Available online 25 September 2020Source: Physiology &BehaviorAuthor(s): Zahra Behroozi, Fatemeh Ramezani, Atousa Janzadeh, Behnaz Rahimi, Farinaz Nasirinezhad
Source: Physiology and Behavior - Category: Physiology Source Type: research
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