Is Serum Phosphate Concentration a Biomarker for Renal Injury and Recovery in Cardiac Surgery?

ACUTE KIDNEY INJURY (AKI) after cardiac surgery on cardiopulmonary bypass (CPB) is associated with increased hospital length of stay and perioperative morbidity and mortality. Preoperative risk factors include chronic kidney disease (CKD), heart failure with reduced ejection fraction, diabetes, hypertension, anemia, nephrotoxic drugs, and a higher Euroscore II. Perioperative risk factors include prolonged CPB and aortic cross-clamp time, hypotension, low- cardiac- output state, and hemorrhage.1,2 AKI is diagnosed using the Kidney Disease: Improving Global Outcome (KDIGO) criteria based on oliguria and elevation in serum creatinine (SCr) concentration relative to baseline.

Source: Journal of Cardiothoracic and Vascular Anesthesia - July 31, 2020 Category: Anesthesiology Authors: Suneel Ramesh Desai, Nian Chih Hwang Tags: Editorial Source Type: research