Predicting the Effect of Laser Peripheral Iridotomy

Condition:   Glaucoma Interventions:   Other: pupillary block group;   Other: plateau iris group;   Other: mixing mechanism group Sponsor:   Zhongshan Ophthalmic Center, Sun Yat-sen University Recruiting
Source: - Category: Research Source Type: clinical trials

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To investigate whether progressive macular ganglion cell –inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) thinning are predictive for detecting visual field (VF) progression in eyes with high myopia.
Source: American Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Original Articles Source Type: research
Getting the ball rolling for everyone.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Ophthalmology: Eye Physicians & Surgeons Source Type: forums
AbstractGlaucoma is an optic neuropathy that gradually steals the patient's sight by damaging the optic nerve head (which is responsible for transferring images from the eye to the brain). Causing an estimated 12.3% of global blindness, glaucoma is considered as the first leading cause of irreversible blindness in the world. This paper presents a novel eye fundus image analysis algorithm for the automatic measurement of fundus related glaucoma indicators; Cup to Disc Ratio (CDR), verification of the ISNT rule, Disc Damage Likelihood Scale (DDLS), and the classification of the input fundus into glaucoma or non-glaucoma case...
Source: Australasian Physical and Engineering Sciences in Medicine - Category: Biomedical Engineering Source Type: research
Acute angle-closure glaucoma (AACG) caused by vitreous hemorrhage is a rare complication of intravitreal injection that often leads to permanent vision loss without prompt treatment.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Ultrasound in Emergency Medicine Source Type: research
Micro-invasive glaucoma surgery (MIGS) is a potentially safer and more efficacious method studied in patients with mild-to-moderate open-angle glaucoma (OAG) requiring less invasive treatment goals; however, the literature on MIGS must be thoroughly evaluated. We conducted a review of MIGS by searching MEDLINE, EMBASE, and Cochrane CENTRAL. Primary efficacy indicators were reductions in intraocular pressure (IOP) and topical medication use postoperatively. While all comparative randomized controlled trials assessing MIGS in English peer-reviewed journals were included, only observational studies with a target follow-up of ...
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Tags: Major review Source Type: research
Molecules, Vol. 25, Pages 4422: AR12286 Alleviates TGF-β-Related Myofibroblast Transdifferentiation and Reduces Fibrosis after Glaucoma Filtration Surgery Molecules doi: 10.3390/molecules25194422 Authors: Wen-Sheng Cheng Ching-Long Chen Jiann-Torng Chen Le-Tien Lin Shu-I Pao Yi-Hao Chen Da-Wen Lu Scar formation can cause the failure of glaucoma filtration surgery. We investigated the effect of AR12286, a selective Rho-associated kinase inhibitor, on myofibroblast transdifferentiation and intraocular pressure assessment in rabbit glaucoma filtration surgery models. Cell migration and collagen contra...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
ist Human carbonic anhydrases (hCAs) belong to a well characterized group of metalloenzymes that catalyze the conversion of carbonic dioxide into bicarbonate. There are currently 15 known human isoforms of carbonic anhydrase with different functions and distribution in the body. This links to the relevance of hCA variants to several diseases such as glaucoma, epilepsy, mountain sickness, ulcers, osteoporosis, obesity and cancer. This review will focus on two of the human isoforms, hCA I and hCA II. Both are cytosolic enzymes with similar topology and 60% sequence homology but different catalytic efficiency and stabilit...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
CONCLUSION: MIGS can increase the outflow facility of the eye in patients with glaucoma. Though ELT had the lowest impact on the aqueous outflow among the studied procedures in this study. The new test can help in the evaluation of current and further development of new MIGS in the future. PMID: 32967033 [PubMed - as supplied by publisher]
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
Condition:   Glaucoma, Angle-Closure Interventions:   Procedure: Phacoemulsification;   Procedure: Endoscopic cyclophotocoagulation Sponsor:   King Khaled Eye Specialist Hospital Recruiting
Source: - Category: Research Source Type: clinical trials
Authors: Wang LJ, Wang XZ, Li ZM, Kou D, Zhang D, Xu ZZ Abstract OBJECTIVE: The aim of this study was to explore the effect of micro ribonucleic acid (miR)-126 on the apoptosis of retinal ganglion cells in glaucoma rats via the vascular endothelial growth factor (VEGF)-Notch signaling pathway. MATERIALS AND METHODS: A total of 36 Sprague-Dawley (SD) rats were randomly divided into three groups, including normal group (n=12), model group (n=12) and miR-126 antagomir group (n=12). Rats in normal group did not receive any treatment. In model group and miR-126 antagomir group, the rats were used to establish glauco...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
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