This ER doctor and heart transplant survivor wants you to wear a mask

Dr. Alin Gragossian gets it. Wearing a mask, social distancing, frequently washing your hands, using a sanitizing gel or wipe on everything you touch -- all that gets old, fast.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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Authors: Ghali MGZ, Stewart R, Ghali GZ, Blitzer W Abstract Facile identification of cardiac allograft vasculopathy (CAV), extensively prevalently identifiable across recipients of cardiac explanted allografts, has proven challenging using non-invasive modalities exclusively. We consequently sought to evaluate diagnostic precision and accuracy of two-dimensional speckle tracking echocardiography (2D-STE) to the end of detecting international society heart &lung transplantation stage III graft vasculopathy (ISHLT-CAV3) in individuals having received cardiac allografts by the meritorious pre-mortem scripted or ve...
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
Publication date: October 2020Source: IJC Heart &Vasculature, Volume 30Author(s): R.O. Ohiomoba, Q.R. Youmans, P.W. Akanyirige, A.U. Ezema, A.S. Anderson, A. Bryant, K. Jackson, E. Mandieka, D.T. Pham, Y. Raza, J.D. Rich, C.W. Yancy, I.S. Okwuosa
Source: IJC Heart and Vasculature - Category: Cardiology Source Type: research
Patients with preformed antibodies against Human Leukocyte Antigens (HLA) wait longer for a transplant, have higher mortality on the waitlist and worse overall prognosis [1, 2]. There however remains some doubt regarding the impact of elevated pre-transplant panel reactive antibody activity (PRA) on post-transplant risk of rejection and survival [3, 4]. Historically, a PRA value greater than 25% was shown to be associated with decreased long-term survival based on data from both single center and larger UNOS/OPTN registry analysis [1, 3].
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research
We describe the case of an 18‐year‐old male patient, affected by DMD and in a wheelchair from the age of 11. He progressively developed dilated cardiomyopathy, and in 2016, at the age of 14 years, he underwent HeartWare LVAD implantation, as destination therapy, without post‐operative complications. He has been followed up for 47 consecutive months; and 30 months after LVAD implantation, he developed an infection of the exit site, treated by antibiotics and surgical toilette. Following this event, on the basis of patient's good general conditions and willingness, we started to consider heart transplant as a...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Case Report Source Type: research
Conclusions: POLVAD-MEV paracorporeal pulsatile pumps present a safe option for long-term circulatory support in a selected group of patients. Therapy requires pump exchange but enables survival while awaiting a heart transplant. PMID: 32728373 [PubMed]
Source: Polish Journal of Cardio-Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Tags: Kardiochir Torakochirurgia Pol Source Type: research
Conclusions: DCM and ICM are considered the most prevalent underlying diseases in heart transplant candidates. Ejection fraction reached normal ranges following transplant, which provides good quality of life. Low incidence of severe acute rejection demonstrates the effectiveness of our immunosuppressive therapy. In the cases of increased rejection, the patient's immunosuppressive regimen was re-assessed accordingly. PMID: 32728361 [PubMed]
Source: Polish Journal of Cardio-Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Tags: Kardiochir Torakochirurgia Pol Source Type: research
Objectives: To evaluate the value of cardiac power output index (CPOi) in predicting severe primary graft dysfunction (PGD) after heart transplantation (defined as mechanical circulatory support [MCS] and/or mortality
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Original Article Source Type: research
Only a very small portion of end-stage organ failures can be treated by transplantation because of the shortage of donor organs. Although artificial long-term organ support such as ventricular assist devices provide therapeutic options serving as a bridge-to-transplantation or destination therapy for end-stage heart failure, suitable long-term artificial lung systems are still at an early stage of development. Although a short-term use of an extracorporeal lung support is feasible today, the currently available technical solutions do not permit the long-term use of lung replacement systems in terms of an implantable artifi...
Source: ASAIO Journal - Category: Medical Devices Tags: Review Article Source Type: research
This study reports the first analysis regarding cost-effectiveness of left ventricular assist device (LVAD) implantation via thoracotomy. Cost-effectiveness of LVADs implanted via the traditional surgical approach of sternotomy has been improved through the years because of technological advances, along with understanding the importance of patient selection and postimplant management have on positively affecting outcomes. Given the positive clinical outcomes of the thoracotomy approach, we seek to study the cost-effectiveness of a centrifugal LVAD via this less invasive approach. We developed a Markov model. Survival and q...
Source: ASAIO Journal - Category: Medical Devices Tags: Adult Circulatory Support Source Type: research
There is limited data on the cost-effectiveness of continuous-flow left ventricular assist devices (LVAD) in the United States particularly for the bridge-to-transplant indication. Our objective is to study the cost-effectiveness of a small intrapericardial centrifugal LVAD compared with medical management (MM) and subsequent heart transplantation using the respective clinical trial data. We developed a Markov economic framework. Clinical inputs for the LVAD arm were based on prospective trials employing the HeartWare centrifugal-flow ventricular assist device system. To better assess survival in the MM arm, and in the abs...
Source: ASAIO Journal - Category: Medical Devices Tags: Adult Circulatory Support Source Type: research
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