Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.

CONCLUSION: UA232 induced apoptosis through the ER stress pathway, and showed stronger growth-inhibitory effects in A549 and H460 cells compared to UA, which may be a potential anticancer drug to suppress the proliferation of lung cancer. PMID: 32726164 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32726164?dopt=Abstract

Source: Pharmaceutical Biology - July 31, 2020 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research