How to live longer: A plant known to reduce the risk of cancer to boost life longevity
HOW TO live longer: When it comes to living a longer and healthier life, most are well aware of what foods and drinks to stay away from. When it comes to what we should be consuming more of, there is a bit of confusion. According to experts, eating more of this type of plant will help to reduce cancer risk and boost your longevity.
Publication date: 1 October 2020Source: Life Sciences, Volume 258Author(s): Cynthia Aslan, Sepideh Maralbashi, Houman Kahroba, Milad Asadi, Mohammad Sadegh Soltani-Zangbar, Mahsa Javadian, Dariush Shanehbandi, Behzad Baradaran, Masood Darabi, Tohid Kazemi
Publication date: 1 October 2020Source: Life Sciences, Volume 258Author(s): Mahdi Abdoli Shadbad, Khalil Hajiasgharzadeh, Behzad Baradaran
Abstract MicroRNAs (miRNAs) are a class of ~22 nt noncoding RNAs playing essential roles in the post-transcriptional regulation of gene expression, cell proliferation, and cell differentiation and are often found deregulated in several diseases including cancer.The A-to-I RNA editing, mediated by ADAR enzymes, is a diffuse post-transcriptional mechanism that converts the genetically coded adenosine (A) into inosine (I) at the RNA level. Among different RNA targets, the ADAR enzymes can also edit miRNA precursors. Specifically, a single nucleotide change (A/I) lying within the mature miRNA can alter ...
The objective of the current investigation was to develop and evaluate the passive targeting of long-circulating PLGA NPs loaded with BRU. NPs were characterized in terms of drug-excipient compatibility studies, including FTIR and DSC; physicochemical evaluations including particle size, zeta potential, morphological evaluation, entrapment efficiency and percentage yield; total serum protein adsorbed onto NP surfaces; and in vitro release of the loaded drug. Factorial design was employed to attain optimal PLGA-loaded NPs. Finally, the in vivo anti-tumor activity of BRU-loaded PLGA NPs was evaluated in tumor-beari...
Publication date: Available online 31 July 2020Source: Process BiochemistryAuthor(s): Rizwan Wahab, Quaiser Saquib, Mohammad Faisal
Publication date: December 2020Source: Colloids and Surfaces B: Biointerfaces, Volume 196Author(s): Chaiyakarn Pornpitchanarong, Theerasak Rojanarata, Praneet Opanasopit, Tanasait Ngawhirunpat, Prasopchai Patrojanasophon
Publication date: Available online 1 August 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Paweena Dana, Suphawadee Bunthot, Kunat Suktham, Suvimol Surassmo, Teerapong Yata, Katawut Namdee, Werayut Yingmema, Thunyatorn Yimsoo, Uracha Rungsardthong Ruktanonchai, Sith Sathornsumetee, Nattika Saengkrit
Publication date: Available online 29 July 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Mengyao Liu, Manfei Fu, Xiaoye Yang, Guoyong Jia, Xiaoqun Shi, Jianbo Ji, Xianghong Liu, Guangxi Zhai
Publication date: Available online 29 July 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Shouning Yang, Yanmin Zhang, Sijia Lu, Lihong Liu, Lin Yang, Yuming Guo, Shaoning Yu, Huayan Yang
Publication date: Available online 31 July 2020Source: TrAC Trends in Analytical ChemistryAuthor(s): Yaser Pashaei, Mona Mehrabi, Maryam Shekarchi