Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants
This study highlights ASoC as a functional mechanism of noncoding neuropsychiatric risk variants, providing a powerful framework for identifying disease causal variants and genes.
Source: ScienceNOW - Category: Science Authors: Zhang, S., Zhang, H., Zhou, Y., Qiao, M., Zhao, S., Kozlova, A., Shi, J., Sanders, A. R., Wang, G., Luo, K., Sengupta, S., West, S., Qian, S., Streit, M., Avramopoulos, D., Cowan, C. A., Chen, M., Pang, Z. P., Gejman, P. V., He, X., Duan, J. Tags: Genetics, Medicine, Diseases reports Source Type: news
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