TOMM40 and APOE variants synergistically increase the risk of Alzheimer's disease in a Chinese population.

CONCLUSIONS: This study provides invaluable insights into the mechanisms underlying the prevalence of AD in Chinese populations, and supports that simultaneous TOMM40 and APOE genotyping in the clinical setting may identify individuals at high risk of developing AD. PMID: 32725468 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32725468?dopt=Abstract

Source: Aging Clinical and Experimental Research - July 27, 2020 Category: Geriatrics Authors: Zhu Z, Yang Y, Xiao Z, Zhao Q, Wu W, Liang X, Luo J, Cao Y, Shao M, Guo Q, Ding D Tags: Aging Clin Exp Res Source Type: research