SNHG7 Facilitates Glioblastoma Progression by Functioning as a Molecular Sponge for MicroRNA-449b-5p and Thereby Increasing MYCN Expression.

CONCLUSION: In summary, our results demonstrated that small nucleolar RNA host gene 7 regulates glioblastoma proliferation, migration, and invasion via regulating miR-449b-5p and its target gene MYCN, thereby providing a potential therapeutic target for glioblastoma.
PMID: 32720593 [PubMed - in process]

Source: Technology in Cancer Research and Treatment - December 31, 2019 Category: Cancer & Oncology Authors: Chen Y, Yuan S, Ning T, Xu H, Guan B Tags: Technol Cancer Res Treat Source Type: research