Intramural coronary light-chain amyloidosis and left ventricular assist device implantation

Light-chain (AL) amyloidosis with cardiac involvement is largely because of interstitial amyloid infiltration resulting in a thickened left ventricle (LV) and restrictive hemodynamics. However, amyloid protein can be deposited mainly in the coronary microvasculature, with resultant ischemia and cardiogenic shock.1,2 Left ventricular assist devices (LVADs) are not often considered in patients with AL cardiac amyloidosis because of a small LV size and ongoing chemotherapy.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: CASE ANECDOTES, COMMENTS AND OPINIONS Source Type: research