Quantification of 3-Hydroxypropyl Mercapturic Acid in the Urine of Patients with Breast Cancer to Monitor Cyclophosphamide Toxicity

Conclusions: The method was applicable for the quantification of 3-HPMA in human urine. Large variations in 3-HPMA concentrations were found in 40 patients with breast cancer treated with cyclophosphamide, with a significant difference (P
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Focus Series: Therapeutic Drug Monitoring in Oncology Source Type: research