Extranodal NK/T cell lymphoma.

Extranodal NK/T cell lymphoma. Blood Res. 2020 Jul 31;55(S1):S63-S71 Authors: Jeong SH Abstract Extranodal natural killer (NK)/T cell lymphoma (ENKTL) is a distinct subtype of Non-Hodgkin's lymphoma mainly involving the nasal area. Since the entity was first recognized, treatment strategies have been evolving from anthracycline-based chemotherapy and radiotherapy to L-asparaginase containing regimens and recently immune checkpoint inhibitors. With the currently used combined chemotherapy and radiotherapy, more than 70% of patients with localized disease can be cured. L-asparaginase containing regimens have significantly improved treatment outcomes among patients with advanced disease. However, the treatment outcomes of patients with disease refractory to L-asparaginase containing regimens or who experience recurrence remain poor. In this article, we cover the current treatments for ENKTL and emerging treatment approaches. PMID: 32719179 [PubMed]
Source: Blood Research - Category: Hematology Tags: Blood Res Source Type: research