Structural elucidation of V ‐type nerve agents by liquid chromatography/electrospray ionization mass spectrometry

We present a simple approach for their structural elucidation based on two complementary experiments: ESI‐MS/MS of the original compound, which provides information about the amine moiety, and ESI‐MS/MS of the phosphonic acid hydrolysis products generated byN‐iodosuccinimide, which provides ions' characteristic of the phosphonate structure. This approach enables the structural elucidation of the original V‐agents with a higher degree of certainty.

Source: Journal of Mass Spectrometry - July 27, 2020 Category: Chemistry Authors: Tamar Shamai Yamin, Hagit Prihed, Moran Madmon, Merav Blanca, Avi Weissberg Tags: APPLICATION NOTE Source Type: research