Drug Burden Index and Cognitive and Physical Function in Aged Care Residents: A Longitudinal Study

Anticholinergic/antimuscarinic and sedative medications (eg, benzodiazepines) have been found to be associated with poorer cognitive and physical function and mobility impairment in older age. However, previous studies were mostly conducted among community-dwelling older individuals and had often a cross-sectional design. Accordingly, our aim was to examine longitudinal associations between cumulative exposure to anticholinergic and sedative medications and cognitive and physical function among residents from aged care homes.

Source: Journal of the American Medical Directors Association - July 29, 2020 Category: Health Management Authors: Hans Wouters, Sarah N. Hilmer, Jos Twisk, Martina Teichert, Helene G. Van Der Meer, Hein P.J. Van Hout, Katja Taxis Tags: Original Study Source Type: research