Sleeve gastrectomy ameliorated high-fat diet (HFD)-induced non-alcoholic fatty liver disease and upregulated the nicotinamide adenine dinucleotide  +/ Sirtuin-1 pathway in mice.

CONCLUSION: SG significantly alleviated NAFLD in HFD-induced obese mice with increasing the hepatic NAD + levels and upregulating the NRK1/NAD+/SIRT1 pathway.
PMID: 32712045 [PubMed - as supplied by publisher]

Source: Asian Journal of Surgery - July 21, 2020 Category: Surgery Authors: Hua R, Wang GZ, Shen QW, Yang YP, Wang M, Wu M, Shao YK, He M, Zang Y, Yao QY, Zhang ZY Tags: Asian J Surg Source Type: research