Correlation between the HIF-1 α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain

The HIF-1 α/Notch signaling pathway regulates cell proliferation, apoptosis, and metabolism in the intervertebral discs (IVDs) and is implicated in disc degeneration. The nucleus pulposus (NP) is an important s...

Source: BMC Musculoskeletal Disorders - July 28, 2020 Category: Orthopaedics Authors: Zekang Xiong, Jun Ding, Jinge Zhou, Sheng Yao, Jin Zheng and Xiaodong Guo Tags: Research article Source Type: research