Contribution of Serotonin 3A Receptor to Motor Function and Its Expression in the Gastrointestinal Tract

Conclusions: These results show that 5-HT3AR is highly expressed in the stomach and large intestine and that the activation of 5-HT3AR accelerates gastric emptying and large intestine transit. Additionally, 5-HT3AR is highly expressed in cholinergic neurons and some interstitial cells, such as PDGFR α+ cells.Digestion
Source: Digestion - Category: Gastroenterology Source Type: research