The emerging role of lncRNAs in multiple sclerosis
Multiple sclerosis (MS) is the most common inflammatory demyelinating disease of the central nervous system (CNS) with various clinical manifestations. The characteristic of MS is that myelin is attacked by the body's immune system and increases the electrical capacity of axons, and is the primary pathophysiological mechanism of the transmission block. Studies have shown that epigenetic factors participate in the development of MS. LncRNAs are highly abundant and heterogeneous linear RNA transcripts with lengths exceeding 200 nucleotides and no protein-coding potential.
Source: Journal of Neuroimmunology - Category: Allergy & Immunology Authors: Samin Ghaderian, Navid Shomali, Soheil Behravesh, Gholamreza Rezaei Danbaran, Maryam Hemmatzadeh, Saeed Aslani, Farhad Jadidi-Niaragh, Ramin Hosseinzadeh, Shahram Torkamandi, Hamed Mohammadi Tags: Review Article Source Type: research