Maternal hypertension-related genotypes and congenital heart defects.

CONCLUSIONS: We replicated a previously reported association between rs633185 and conotruncal defects. Although additional hypertension-related SNPs were also associated with congenital heart defects, more work is needed to better understand the relationship between genetic risk for maternal hypertension and congenital heart defects occurrence.
PMID: 32710738 [PubMed - as supplied by publisher]

Source: American Journal of Hypertension - July 24, 2020 Category: Cardiology Authors: Lei Y, Ludorf KL, Yu X, Benjamin RH, Gu X, Lin Y, Finnell RH, Mitchell LE, Musfee FI, Malik S, Canfield MA, Morrison AC, Hobbs CA, Van Zutphen AR, Fisher S, Agopian AJ, National Birth Defects Prevention Study Tags: Am J Hypertens Source Type: research