In-vitro and in-vivo anti-breast cancer activity of synergistic effect of berberine and exercise through promoting the apoptosis and immunomodulatory effects.

CONCLUSIONS: These results indicate that the synergistic treatment of exercise and BBR can improve the immune system, regulate intestinal microbial metabolite (SCFA), activate the mitochondrial apoptosis pathway and Fas death receptor apoptosis pathway, and thus play an anticancer role. This may provide a new method for the treatment of breast cancer.
PMID: 32707493 [PubMed - as supplied by publisher]

Source: International Immunopharmacology - July 20, 2020 Category: Allergy & Immunology Authors: Ma W, Zhang Y, Yu M, Wang B, Xu S, Zhang J, Li X, Ye X Tags: Int Immunopharmacol Source Type: research