Injection of CD40 DNA vaccine ameliorates the autoimmune pathology of Non-obese Diabetic Mice with Sj ögren's Syndrome.

CONCLUSIONS: CD40 DNA vaccine inhibits the immune response and reduce inflammation in epithelial tissues SS in non-obese diabetic (NOD) mice, suggesting that CD40 DNA vaccine could be a new therapeutic approach in treatment of pSS.
PMID: 32707129 [PubMed - as supplied by publisher]

Source: Immunology Letters - July 20, 2020 Category: Allergy & Immunology Authors: Zhou YB, Yuan X, Wang QK, Zhang H, Wang GS, Li XP, Wang Y, Harris D, Li XM Tags: Immunol Lett Source Type: research