Prevalence and abundance of selected genes conferring macrolide resistance genes in COPD patients during maintenance treatment with azithromycin

ConclusionsThe acquisition rate of macrolide resistance genes in COPD patients treated with azithromycin maintenance therapy was limited, but the relative abundance of macrolide resistance genes increased significantly over time compared to placebo.This study was part of the COLUMBUS trial (Clinicaltrials.gov,NCT00985244).
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research