Molecular Characterization of Hepatitis C Virus for Subtype Determination and Resistance-Associated Substitutions Detection among Chinese Voluntary Blood Donors.

CONCLUSIONS: Low genetic barriers facilitated the generation of resistance mutants and threated the efficacy of DAA regimens. The baseline RASs posed a great challenge to real-world DAA application.
PMID: 32717286 [PubMed - as supplied by publisher]

Source: Antiviral Research - July 23, 2020 Category: Virology Authors: Jiang X, Lv X, Chang L, Yan Y, Ji H, Sun H, Guo F, Rodgers MA, Yin P, Wang L Tags: Antiviral Res Source Type: research