Serum Galactomannan Versus a Combination of Galactomannan and Polymerase Chain Reaction-Based Aspergillus DNA Detection for Early Therapy of Invasive Aspergillosis in High-Risk Hematological Patients: A Randomized Controlled Trial

Conclusions. A combined monitoring strategy based on serum GM and Aspergillus DNA was associated with an earlier diagnosis and a lower incidence of IA in high-risk hematological patients.
Clinical Trials Registration. NCT01742026.

Source: Clinical Infectious Diseases - January 13, 2015 Category: Infectious Diseases Authors: Aguado, J. M., Vazquez, L., Fernandez-Ruiz, M., Villaescusa, T., Ruiz-Camps, I., Barba, P., Silva, J. T., Batlle, M., Solano, C., Gallardo, D., Heras, I., Polo, M., Varela, R., Vallejo, C., Olave, T., Lopez-Jimenez, J., Rovira, M., Parody, R., Cuenca-Estr Tags: ARTICLES AND COMMENTARIES Source Type: research