EP News: Basic and Translational

In the current article, Zheng et  al (Nat Rev Cardiol 2020;17:259–260, PMID 32139904) provide an up-to-date review of 2019 coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 infects host cells using the host receptor angiotensin-converting enzyme 2 (AC E2). In patients with COVID-19, the incidence of cardiovascular involvement is high, although the specific mechanisms remain uncertain. The mechanism may be related to ACE2, which is expressed not only in the lungs but also in the cardiovascular system; therefore, ACE2-related signaling pathways mig ht also play a role in cardiac injury.
Source: Heart Rhythm - Category: Cardiology Authors: Tags: EP News Source Type: research