Natural History and Disease Progression of Early Cardiac Amyloidosis Evaluated by Echocardiography

Since the diagnosis of cardiac amyloidosis (CA) is often delayed, echocardiographic findings are frequently indicative of advanced cardiomyopathy. We aimed to describe early echocardiographic features in patients subsequently diagnosed with CA. Pre-amyloid diagnosis echocardiographic studies were screened for structural and functional parameters and stratified according to the pathogenetic subtype (immunoglobulin light-chain (AL) or amyloid transthyretin (ATTR)). Abnormalities were defined based on published guidelines.

Source: The American Journal of Cardiology - July 26, 2020 Category: Cardiology Authors: Osnat Itzhaki Ben Zadok, Alon Eisen, Yaron Shapira, Daniel Monakier, Zaza Iakobishvili, Shmuel Schwarzenberg, Aryeh Abelow, Hadass Ofek, Shirit Kazum, Binyamin Ben-Avraham, Ashraf Hamdan, Tamir Bental, Alik Sagie, Ran Kornowski, Mordehay Vaturi Source Type: research