4,5-Diaryl imidazoles with hydroxamic acid appendages as anti-hepatoma agents

Conclusions The new imidazolyl hydroxamic acids lend themselves as a possible alternative to SAHA in the therapy of HCC. Even more so since similar 4,5-diarylimidazoles lacking only the hydroxamate functionality were previously shown in animal studies to be well tolerated and orally applicable.
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research