A New Austalide from Penicillium sp. SO01

Five austalide meroterpenoids, including a new one named 13-deoxyaustalide Q acid methyl ester, were isolated from the ethyl acetate extract of the fungusPenicillium sp. SO01. The structure of the new compound was determined on the basis of IR, UV, HR-ESI-MS NMR spectra and CD data. The cytotoxicities of compound1 against three human tumor cell lines were also tested, with IC50 values of 27.66 μM (SW-1990 cell line), 28.77 μM (Hep3B cell line), and 39.93 μM (HepG2 cell line).
Source: Chemistry of Natural Compounds - Category: Chemistry Source Type: research
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