Subcortical atrophy correlates with the Perturbational Complexity Index in patients with disorders of consciousness

The complexity of neurophysiological brain responses to direct cortical stimulation, referred to as the perturbational complexity index (PCI), has been shown able to discriminate between consciousness and unconsciousness in patients surviving severe brain injury as well as several other conditions (e.g., wake, dreamless sleep, sleep and ketamine dreaming, anesthesia).

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 23, 2020 Category: Neurology Authors: Evan S. Lutkenhoff, Micah A. Johnson, Silvia Casarotto, Marcello Massimini, Martin M. Monti Source Type: research