Is There an Additional Value in Detecting Anticardiolipin and Anti- β2 glycoprotein I IgA Antibodies in the Antiphospholipid Syndrome?

CONCLUSION:  aCL and aβ2GPI IgA are associated with clinical manifestations of APS. However, isolated IgA positivity was rare and not associated with thrombosis or pregnancy morbidity. These data do not support testing for aCL and aβ2GPI IgA subsequent to conventional aPL assays in identifying patients with thrombosis or pregnancy morbidity.
PMID: 32696448 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - July 20, 2020 Category: Hematology Authors: Chayoua W, Yin DM, Kelchtermans H, Moore GW, Gris JC, Musiał J, Zuily S, Ten Cate H, de Laat B, Devreese KMJ Tags: Thromb Haemost Source Type: research