Gastric per-oral endoscopic myotomy for severe post-lung transplant gastroparesis: A single-center experience

Gastroparesis is frequently identified after lung transplantation with incidence rates as high as 44%.1 Gastroparesis after lung transplantation is of significant concern because complications directly related to gastroparesis, specifically gastroesophageal reflux and aspiration, have been linked to the development of bronchiolitis obliterans syndrome, the primary cause of graft failure and the main cause of late morbidity and mortality following lung transplantation.1 The therapy for medically refractory post-lung transplant gastroparesis represents a significant therapeutic challenge because current therapies (such as botulinum toxin injection or surgical pyloromyotomy/bypass) are either limited by inconsistent efficacy or by their invasiveness.

Source: The Journal of Heart and Lung Transplantation - July 9, 2020 Category: Transplant Surgery Authors: Alexander J. Podboy, John O. Clarke, Linda A. Nguyen, Joshua J. Mooney, Gundeep S. Dhillon, Joo Ha Hwang Tags: RESEARCH CORRESPONDENCE Source Type: research