Methylphenidate and the risk of burn injury among children with attention-deficit/hyperactivity disorder - Chen VCH, Yang YH, Yu Kuo T, Lu ML, Tseng WT, Hou TY, Yeh JY, Lee CTC, Chen YL, Lee MJ, Dewey ME, Gossop M.

AIMS: Attention-deficit/hyperactivity disorder (ADHD) is associated with a higher risk of burn injury than in the normal population. Nevertheless, the influence of methylphenidate (MPH) on the risk of burn injury remains unclear. This retrospective cohort ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

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We examined the cumulative effect of MPH on burn injury risk using Cox proportional hazards models. We conducted a sensitivity analysis for immortal time bias using a time-dependent Cox model and within-patient comparisons using the self-controlled case series model. RESULTS: Children with ADHD taking MPH had a reduced risk of burn injury, with a cumulative duration of treatment dose-related effect, compared with those not taking MPH. Compared with children with ADHD not taking MPH, the adjusted hazard ratio for burn injury was 0.70 in children taking MPH for
Source: Epidemiology and Psychiatric Sciences - Category: Psychiatry Tags: Epidemiol Psychiatr Sci Source Type: research
Conclusion, do not visit cardiologists. They will give you heart attacks. No, that’s ridiculous. It’s so mind blowing that anyone even said this, right? It’s just ugh. Obviously, people who are extremely sick and who are at risk of killing themselves get psychiatric care. No kidding. So, yeah, this is, in fact, very dangerous. Gabe: The word bullshit is not big enough. This is the literal equivalent of me saying that I looked at fifty thousand people who went to the hospital in the last year. And you were much more likely to die if you had a hospital admission. Now, I’m talking physical health now. ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Mental Health and Wellness Not Crazy Podcast Psychiatry Treatment Source Type: blogs
Source: Neuropsychiatric Disease and Treatment - Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research
Clonidine is a centrally-acting α-2 agonist used in the treatment of hypertension and attention-deficit/hyperactivity disorder, among other off-label uses. In overdose, it can cause sedation, bradycardia, and hypotension. Clonidine can be compounded as a liquid formula for patients who are unable to take pills, however, this can add to the risk of a dosing errors.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Selected Topics: Toxicology Source Type: research
Abstract Questions persist about whether attention deficit hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and conduct disorder are in fact distinct from one another. When such questions arise, ODD is often suggested to be subsumed under one or the other condition. Modeling approaches that can evaluate whether specific subfactors can be distinguished from general psychopathology are of great interest, and the general bifactor model has been increasingly applied in studies evaluating the structure of psychopathology. However, evidence for bias in the model, the frequency of anomalous indicators,...
Source: Journal of Abnormal Child Psychology - Category: Psychiatry & Psychology Authors: Tags: J Abnorm Child Psychol Source Type: research
Applying the Bifactor S-1 Model to Ratings of ADHD/ODD Symptoms: A Commentary on Burns et al. (2019) and a Re-Analysis. J Abnorm Child Psychol. 2020 Mar 31;: Authors: Junghänel M, Rodenacker K, Dose C, Döpfner M Abstract To examine the construct validity of attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD), the bifactor S-1 approach has been applied as an alternative to the fully symmetrical bifactor models in order to eliminate anomalous results and to allow for an unambiguous interpretation of g- and s-factors. We compared and contrasted our resul...
Source: Journal of Abnormal Child Psychology - Category: Psychiatry & Psychology Authors: Tags: J Abnorm Child Psychol Source Type: research
Abstract Burns et al. (this issue) have shown that the application of the symmetrical bifactor model to attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) symptoms leads to anomalous and inconsistent results across different rater groups. In contrast to the symmetrical bifactor model, applications of the bifactor S-1 model showed consistent and theoretically well-founded results. The implications of the bifactor S-1 model for individual clinical assessment are discussed. It is shown that individual factor scores of the bifactor S-1 model reveal important information about the p...
Source: Journal of Abnormal Child Psychology - Category: Psychiatry & Psychology Authors: Tags: J Abnorm Child Psychol Source Type: research
Publication date: Available online 29 January 2020Source: Journal of Psychiatric ResearchAuthor(s): Joseph W. Fredrick, Michael J. Kofler, Matthew A. Jarrett, G. Leonard Burns, Aaron M. Luebbe, Annie A. Garner, Sherelle L. Harmon, Stephen P. BeckerAbstractRecent theoretical and empirical evidence highlights associations between attention-deficit/hyperactivity disorder (ADHD) symptoms and task-unrelated thought, including mind-wandering and rumination. However, it has been hypothesized that sluggish cognitive tempo (SCT), characterized by daydreaming and staring behaviors, may uniquely relate to task-unrelated thought. The ...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Abstract The symmetrical bifactor model is often applied to attention-deficit/hyperactivity disorder (ADHD)-hyperactive/impulsive (HI), ADHD-inattentive (IN), and oppositional defiant disorder (ODD) symptoms, but this model frequently yields anomalous or inadmissible results. An alternative model, the bifactor S - 1 model, is more appropriate for examining the hierarchical structure of ADHD/ODD symptoms. Both models were applied to ADHD-HI, ADHD-IN, and ODD symptom ratings by mothers, fathers, and teachers for 2142 Spanish children (49.49% girls; ages 8-13 years). The symmetrical bifactor model yielded the ty...
Source: Journal of Abnormal Child Psychology - Category: Psychiatry & Psychology Authors: Tags: J Abnorm Child Psychol Source Type: research
ConclusionsThese results support using the ADHD R-S to capture comorbid ADHD symptoms in ASD. The findings underscore the need for more thorough examination of inattentive symptoms to rule out ADHD-I.
Source: Research in Autism Spectrum Disorders - Category: Psychiatry Source Type: research
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