Preconditioning with L-Ala-Gln reduces the expression of inflammatory markers (TNF- α, NF-κB, IL-6 and HO-1) in an injury animal model of cerebrovascular ischemia in Meriones unguiculatus (gerbils).

Conclusion These findings suggest a protective effect of L-Ala-Gln by decreasing levels of TNF-alpha, IL-6 and NF-κB and Increasing levels of HO-1. PMID: 32696813 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32696813?dopt=Abstract

Source: Acta Cirurgica Brasileira - July 23, 2020 Category: Surgery Authors: Oliveira LRA, Albuquerque AO, Silva CISM, Silva JM, Casadevall MQFC, Azevedo OGR, Albuquerque VLSP, Vasconcelos PRL Tags: Acta Cir Bras Source Type: research