Very preterm birth results in later lower platelet activation markers.

CONCLUSIONS: Very preterm birth was associated with decreased markers of platelet activation among preschoolers. These findings are consistent with reduced platelet reactivity persisting from very preterm birth to a preschool age. IMPACT: Former very preterm-born preschoolers featured reduced levels of platelet activation markers.While lower platelet reactivity in very preterm-born compared to term-born infants in the first days of life was established, it was unknown when, if at all, reactivity normalizes. The current study suggests that platelet hyporeactivity due to very preterm birth persists at least up to a preschool age."Immaturity of the hemostatic system" may be a persistent sequel of preterm birth, but larger studies are needed to investigate its potential clinical implications. PMID: 32698194 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32698194?dopt=Abstract

Source: Pediatric Research - July 21, 2020 Category: Pediatrics Authors: Pechlaner R, Posod A, Yin X, Burnap SA, Kiechl SJ, Mayr M, Kiechl S, Kiechl-Kohlendorfer U Tags: Pediatr Res Source Type: research