Progress on Mechanism of MET Gene Mutation and Targeted Drugs in Non-small Cell Lung Cancer

The objective response rate of MET inhibitors is high, and the safety is good. However, resistance of MET-tyrosine kinase inhibitor (TKI) is inevitable, so it is necessary to pay attention to the study of drug resistance mechanism. In addition, the combined use of hepatocyte growth factor (HGF)/MET inhibitors and other drugs may play an important role in inhibiting and reversing drug resistance. DOI: 10.3779/j.issn.1009-3419.2020.102.32
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research