Scientific diligence for oncology drugs: a pharmacology, translational medicine and clinical perspective.
Scientific diligence for oncology drugs: a pharmacology, translational medicine and clinical perspective.
Drug Discov Today. 2020 Jul 18;:
Authors: Parasrampuria DA, Bandekar R, Puchalski TA
Abstract
Increasingly, new drug development by major pharma companies relies on in-licensing of innovative therapies. Often there are limited data accompanying these novel entities. By focusing on scientific principles and generating key preclinical and clinical data, discovery companies can improve their valuations. From the lens of large pharma, we highlight key scientific aspects that are assessed to mitigate risk in valuations and deal terms. Our focus is on clinical development aspects for oncology drugs by stage of development. However, these lessons apply equally to other therapeutic areas.
PMID: 32693162 [PubMed - as supplied by publisher]
Source: Drug Discovery Today - Category: Drugs & Pharmacology Authors: Parasrampuria DA, Bandekar R, Puchalski TA Tags: Drug Discov Today Source Type: research