Nutrients men-TOR β-Cells to Adulthood.

Nutrients men-TOR β-Cells to Adulthood. Dev Cell. 2020 Jul 20;54(2):140-141 Authors: Katsumoto K, Grapin-Botton A Abstract A major trigger of adult β-cell insulin secretion is glucose. In a recent issue of Cell Metabolism, Helman and colleagues show that in fetuses insulin secretion depends on the activation of mTOR by amino acids and that reducing amino acids promotes maturation of β-cells derived from pluripotent stem cells. PMID: 32693054 [PubMed - in process]
Source: Developmental Cell - Category: Cytology Authors: Tags: Dev Cell Source Type: research