Identifying Pleiotropic SNPs Associated With Femoral Neck and Heel Bone Mineral Density

ConclusionMost of SNPs or putative causal SNPs associated with FNK-BMD were also associated with eBMD. However, most of SNPs or putative causal SNPs associated with eBMD were not associated with FNK-BMD. The novel variants we identified may help to account for the additional proportion of variance of each trait and advance our understanding of the genetic mechanisms underlying osteoporotic fracture.
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research