General anesthesia adds to the cognitive sequelae of childhood cancer

The impact of the total number of administrations and the cumulative dosage of anesthetics and sedatives on the developing brain is not a new topic for readers of The Journal (J Pediatr 2019;204:285 –90). In this volume, Jacola et al report the effects of anesthesia exposure in 111 children with medulloblastoma from a retrospective, secondary analysis of patients at St. Jude Children's Research Hospital enrolled on a multisite clinical trial (https://clinicaltrials.gov/ct2/show/NCT00085202). The children were all treated with surgical resection of tumor, followed by radiotherapy and chemotherapy.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: The Editors' Perspectives Source Type: research