A clinical scoring system to predict long-term arthralgia in Chikungunya disease: A  cohort study

by Laise de Moraes, Thiago Cerqueira-Silva, Victor Nobrega, Kevan Akrami, Luciane Amorim Santos, Cibele Orge, Paula Casais, Lais Cambui, Rita de C ássia Pontello Rampazzo, Karen Soares Trinta, Camila Amato Montalbano, Maria Jania Teixeira, Luciano Pamplona Cavalcante, Bruno B. Andrade, Rivaldo Venâncio da Cunha, Marco Aurélio Krieger, Manoel Barral-Netto, Aldina Barral, Ricardo Khouri, Viviane Sampaio Boaventura BackgroundChikungunya virus (CHIKV) has caused worldwide epidemics that impose a major burden on health systems. Approximately half of infected individuals develop chronic debilitating arthralgia, affecting their quality of life. Here, we identified the relevant clinical and demographic variables in the acute phase of CHIKV infection prospectively linked to chronic arthralgia to elaborate a prognostic scoring system. MethodsAcute CHIKV infection cases (n = 134) confirmed by serology or molecular test were examined
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research