Reversible Myelofibrosis in Pediatric Renal Osteodystrophy

A 9-year-old female with no medical care for 3 years presented with recurrent emesis, epistaxis, and pallor. Laboratory evaluation showed renal failure with blood urea nitrogen 216 mg/dL and serum creatinine of 17.5 mg/dL. Hematologic workup showed severe normocytic anemia with hemoglobin concentration of 4.3 g/dL and an initial platelet count of 108 x 109/L that decreased to 60 x 109/L over 5 days. Her total white blood cell count was normal, but she had mild lymphopenia (1.3 X 109/L). Parathyroid hormone (PTH) levels were markedly elevated at 1600 pg/mL (normal range 15-87).

Source: The Journal of Pediatrics - July 19, 2020 Category: Pediatrics Authors: Anthony Sabulski, Erica Hughley, Edward J. Nehus, David D. Grier, Omar Niss Tags: Insights and Images Source Type: research