Could brain protein help people 'sleep off' the flu?

Conclusion This complex study suggests the AcPb protein is playing a role in regulating normal sleep and the response to flu infection in mice. At this stage, the implications of this research for humans are unclear, as differences between the species may mean the results would not be exactly the same in humans. While The Telegraph suggests this "could finally lead to an effective treatment for the [flu], which until now has eluded experts", we are a long way off knowing whether this is the case. What the researchers have shown – in mice – is if you remove this protein, mice don't fight the virus as well. This does not necessarily mean giving mice more of the protein would make them fight it better. It also doesn't mean giving more of the protein wouldn't have side effects. Overall, this research is at a very early stage, with much more animal research needed before we know if we are closer to a flu treatment. There is currently no cure for the flu, so the most effective weapon against it is prevention, such as good basic hygiene procedures and the flu jab. The jab is recommended for people who are at risk of developing serious complications if they catch the flu, such as the over 65s, pregnant women, and people with a serious long-term illness. Read about the influenza vaccination and who should get it. Analysis by Bazian. Edited by NHS Choices. Follow Behind the Headlines on Twitter. Join the Healthy Eviden...
Source: NHS News Feed - Category: Consumer Health News Tags: Neurology Medication Heart/lungs Swine flu Source Type: news

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Date: Tuesday, 05 28, 2019; Speaker: Dr. Thuy Ngo, Research Assistant Professor, Oregon Health and Science University; Building 29B; 1H10
Source: NIH Calendar of Events - Category: American Health Source Type: events
Prenatal fever could result in brain function impairments in the offspring. The present study investigated the effect of interleukin-6 (IL-6)-induced maternal fever on the offspring and the involvement of connexin 36 in this process. Pregnant C57BL/6J mice were injected with IL-6 on gestational day 15. The levels of iNOS and COX-2 were measured as an index of neuroinflammation in the brain of newborn pups. Offspring were treated with the connexin 36 (Cx36) inhibitor mefloquine at postnatal day (P)1 –P3 or at P40–P42. Rotarod, grip traction, and foot fault tests were carried out to evaluate the motor behavior of...
Source: Developmental Neuroscience - Category: Neuroscience Source Type: research
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM) Issue: Ahead of print
Source: Clinical Chemistry and Laboratory Medicine - Category: Laboratory Medicine Source Type: research
Publication date: Available online 20 May 2019Source: Veterinary ParasitologyAuthor(s): Rodolfo Cordeiro Giunchetti, Patricia Silveira, Lucilene Aparecida Resende, Jaqueline Costa Leite, Otoni Alves de Oliveira Melo-Júnior, Marina Luiza Rodrigues Alves, Laís Moreira Costa, Daniel Ferreira Lair, Vinícius Rossi Chaves, Ingrid dos Santos Soares, Ludmila Zanandreis de Mendonça, Mariana Ferreira Lanna, Helen Silva Ribeiro, Ana Alice Maia Gonçalves, Bruno Mendes Roatt, Rodrigo Dian Oliveira Aguiar-Soares, Juliana Vitoriano-Souza, Nádia das Dores Moreira, Fernando Augusto Siqueira Mathias...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
Publication date: Available online 20 May 2019Source: Fish &Shellfish ImmunologyAuthor(s): Guo Qiao, Chen Xu, Qirui Sun, De-Hai Xu, Mingming Zhang, Peng Chen, Qiang LiAbstractSoiny mullet (Liza haematocheila) is an important economic fish species in China, but stress and diseases have seriously restricted its culture. There are no effective methods such as vaccines to prevent or control these diseases. Alternative methods should be employed, such as using novel immunostimulant poly-β-hydroxybutyrate (PHB). The present study aimed to evaluate effects of dietary PHB supplementation on the growth, antioxidant enzymes...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
In conclusion, HCQ did not adversely affect placental tissue and may have a protective anti-inflammatory function. Further research is needed to determine the mechanisms of HCQ actions on human placenta and whether they could be utilized to improve pregnancy outcomes.
Source: Reproductive Toxicology - Category: Toxicology Source Type: research
Publication date: Available online 20 May 2019Source: Reproductive ToxicologyAuthor(s): Xin Hu, Shuzhao Li, Piera M. Cirillo, Nickilou Y. Krigbaum, ViLinh Tran, Dean P. Jones, Barbara A. CohnAbstractHigh-resolution metabolomics (HRM) profiling of metabolic fingerprints can improve understanding of how poly and perfluoroalkyl substances (PFASs) induce metabolic alterations of in utero environment and impact fetal health. HRM profiling and quantification of PFASs were performed for 397 maternal perinatal serum samples collected from 1959-1967 in the Child Health and Development Studies (CHDS). We used Metabolome-Wide Associa...
Source: Reproductive Toxicology - Category: Toxicology Source Type: research
After earning a degree in polysomnography, and teaching the subject herself, Moe founded Sleep Health Specialists in 2015. The company educates businesses about the advantages of healthy sleep habits among employees.
Source: Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Among the major drivers of the Antimicrobial Resistance crisis is the misuse and overuse of antibiotics in livestock and feed. Credit: Germán Miranda/IPS. By Tharanga YakupitiyageUNITED NATIONS, May 21 2019 (IPS) Antimicrobial resistance is quickly becoming a global crisis and risks reversing a century of progress in health. Some organisations have already geared up and are tackling the issue from its roots. In a new report, the United Nations Interagency Coordination Group (IACG) on Antimicrobial Resistance estimates that antibiotic resistance could cause 10 million deaths each year by 2050. Already, drug-resistan...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Development & Aid Featured Global Headlines Health IPS UN: Inside the Glasshouse North America Regional Categories Sustainability TerraViva United Nations Antimicrobial resistance (AMR) WHO Source Type: news
[Citizen] Kibondo -Pregnant women giving birth outside health facilities in Kibondo District, Kigoma Region face a fine of between Sh20, 000 and Sh50, 000.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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