Gender difference in the risk of adverse outcomes after diabetic foot disease: A mini review.

Gender difference in the risk of adverse outcomes after diabetic foot disease: A mini review. Curr Diabetes Rev. 2020 Jul 16;: Authors: Seghieri G, De Bellis A, Seghieri M, Gualdani E, Policardo L, Franconi F, Francesconi P Abstract Diabetic foot disease (DFD) is a complication of diabetes mellitus, characterized by multiple pathogenetic factors and bearing a very high burden of disability as well as of direct and indirect costs for individuals or healthcare systems. A further characteristic of DFD is that it is associated with a marked risk of subsequent hospitalizations for incident cardiovascular events, chronic renal failure or of all-cause mortality. Additionally, DFD is strongly linked to the male sex, being much more prevalent among men. However, even if DFD mainly affects males, several past reports suggest that females are disadvantaged as regards the risk of subsequent adverse outcomes. This review aims to clarify this point, attempting to provide an explanation for this apparent oddity: being DFD a typically male complication of diabetes but, seemingly, with a greater load of subsequent consequences for females. PMID: 32674734 [PubMed - as supplied by publisher]
Source: Current Diabetes Reviews - Category: Endocrinology Authors: Tags: Curr Diabetes Rev Source Type: research