Stem Cells: A Golden Therapy for Diabetic Wound.

Stem Cells: A Golden Therapy for Diabetic Wound. Curr Diabetes Rev. 2020 Jul 16;: Authors: Buchade S, Desai S, Bhonde R, Kazi H, Sainani S, Rode K Abstract Diabetes mellitus is the 7 th leading cause of death worldwide. Diabetes can affect the organ systems and lead to serious complication, majorly categorized as macrovascular complications, microvascular complications, and diabetic wound. Foot ulcer develops in 15-25% diabetic patient. In diabetic wound there is impairment in growth factor, neuropeptide, matrix metalloproteinases, angiogenesis, immune system. Many approaches are being experimented to manage this major complication of diabetic foot, but unfortunately with lesser success rate. Stem cell is an upcoming field which is being explored in the world of diabetes. Hence, this review is designed to understand the basic pathogenesis and complications of types of diabetes and the role of stem cells in diabetic wound and the benefits related to it. PMID: 32674735 [PubMed - as supplied by publisher]
Source: Current Diabetes Reviews - Category: Endocrinology Authors: Tags: Curr Diabetes Rev Source Type: research