MiR-196a promoted cell migration, invasion and the epithelial-mesenchymal transition by targeting HOXA5 in osteosarcoma.

CONCLUSIONS: MiR-196a promoted cell metastasis and EMT by targeting the 3'-UTR of HOXA5 mRNA in osteosarcoma. The newly identified miR-196a/HOXA5 axis provides novel insight into the pathogenesis of osteosarcoma. PMID: 32675397 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32675397?dopt=Abstract

Source: Cancer Biomarkers - July 18, 2020 Category: Cancer & Oncology Tags: Cancer Biomark Source Type: research