Paraclinical serum markers as aids in the diagnosis of autoimmune encephalitis

This study investigates the sensitivity of these serum markers in a cohort of 26 patients with AE. TPO-Ab, TG-Ab and ANA (titer ≥1:320) were present in 45%, 35% and 32% of patients tested, respectively. The prevalence of TPO-Ab (11.3%), TG-Ab (10.4%) and ANA ≥1:320 (3.3%) has been previously reported in disease-free populations. Although these antibodies represent non-specific markers of autoimmunity, this study demonstr ated that TPO-Ab, TG-Ab and ANA were significantly elevated in AE compared to disease-free populations (p 
Source: Journal of Neuroimmunology - Category: Allergy & Immunology Authors: Source Type: research