Cascade Access to Carboline Carboxylates from Indolyl Ketoximes and Acrylates via Palladium-Catalyzed C –H Bond Alkenylation/Annulation

Synlett DOI: 10.1055/s-0040-1707192 An efficient palladium-catalyzed C–H bond alkenylation/annulation strategy to access carboline carboxylates from indolyl ketoximes and acrylates through C–C/C–N bond formation is reported. Indolyl ketoximes not only direct ortho-olefination with acrylates, but also undergo an intramolecular N–O bond cleavage/traceless annulation to construct carboline carboxylates straightforwardly in this concise method. [...] © Georg Thieme Verlag Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Synlett - Category: Chemistry Authors: Tags: letter Source Type: research
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